Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-09-01
1993-11-23
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548253, C07D40310, A61K 3141
Patent
active
052644472
ABSTRACT:
A human urinary metabolite of Losartan has been isolated and identified as Structure I: ##STR1## This compound is an active angiotensin II receptor antagonist useful in the treatment of hypertension and congestive heart failure.
REFERENCES:
Wong et al., Eur. J. Pharmacol., 202, 323-330 (1991).
DiPrima Joseph F.
Merck & Co. , Inc.
Nicholson William H.
North Robert J.
Springer David B.
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