Angiotensin derivatives

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Angiotensin; related peptides

Reexamination Certificate

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C530S345000

Reexamination Certificate

active

07378489

ABSTRACT:
An angiotensin derivative comprising at least one angiotensin peptide moiety coupled to a peptide carrier-binding moiety which can be used for therapy and prophylaxis of conditions associated with the renin activated angiotensin system.

REFERENCES:
patent: 4384995 (1983-05-01), Stevens
patent: 5229490 (1993-07-01), Tam
patent: WO 93 08842 (1993-05-01), None
patent: WO 97 16201 (1997-05-01), None
J.M. Peters et al.; “Comparison of four bifunctional reagents for coupling peptides to proteins”; J. Immunological Methods, 1989, vol. 120, pp. 133-143.
K.Y. Kumagaye et al.; “Suppression of a side reaction associated with Nim-benzyloxymethyl group during synthesis of peptides containing cysteinyl residue at the N-terminus”; Peptide Research, 1991, vol. 4, No. 2, pp. 84-87.
Kawabe H et al.; “Characterization of receptors for angiotensin-induced drinking and blood pressure responses in conscius rats using angiotensin analogsextended at the n-terminal”; NEUROENDOCRINOLOGY, 1986, vol. 42, pp. 289-295.
F.S. Tjoeng et al.; “Multiple peptide synthesis using a single support (MPS3)”; International Jounal of Peptide and Protein Research, 1990, vol. 35, pp. 141-146.

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