Angiogenesis inhibitor

Details Angiogenesis inhibitor Angiogenesis inhibitor

2002-11-29

2010-06-22

Andres, Janet L (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S322000

Reexamination Certificate

active

07741346

ABSTRACT:
An object of the present invention is to find new pharmacological actions of urea compounds having structure represented by the general formula [1]. The urea compounds having the structure represented by the general formula [1] have excellent angiogenesis inhibitory actions.[wherein “A” is —(NR4)—, —(CR5R6)— or —O—, “B” is alkylene or alkenylene, R1, R2, R4, R5and R6are hydrogen, alkyl, alkenyl, adamantylalkyl or the like, R3is aryl or an unsaturated heterocycle, and X is oxygen or sulfur].

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