Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution...
Reexamination Certificate
2006-11-20
2008-11-25
Leith, Patricia (Department: 1655)
Drug, bio-affecting and body treating compositions
Plant material or plant extract of undetermined constitution...
C424S773000
Reexamination Certificate
active
07455861
ABSTRACT:
The invention provides an acetone extract, chloroform extract or hexane extract ofAngelicae sinensisand/or the active components purified therefrom, such as n-butylidenephthalide, which are effective in treating cancers.
REFERENCES:
patent: 4613591 (1986-09-01), Aburada et al.
Cheng et al. : Acetone Extract Of Angelica Sinensis Inhibits Proliferation Of Human Cancer Cells Via Inducing Cell Cycle Arrest And Apoptosis. Life Sciences.: vol. 75. Issue 13. 2004. pp. 1579-1596.
Bello et al.: Low-Dose Chemotherapy Combined With An Antiangiogenic Drug Reduces Human Glioma Growth In Vivo.: Cancer Research.: 61. 2001. pp. 7501-7506.
Hamer et al.: The Genomic Profile Of Human Malignant Glioma Is Altered Early In Primary Cell Culture And Preserved In Spheroids.: Oncogene.: 2007. pp. 1-6.
Chang Wen-Liang
Cheng Yeung-Leung
Harn Horng-Jyh
Lin Shinn-Zong
Luo Jiann-Kuan
Buddhist Tzu Chi General Hospital
Leith Patricia
McCormick Melenie
Panitch Schwarze Belisario & Nadel LLP
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