Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2008-04-29
2008-04-29
Carlson, Karen Cochrane (Department: 1656)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C530S350000
Reexamination Certificate
active
07364864
ABSTRACT:
The present invention relates to isolated nucleic acid sequences of ANGE, CLLD8 and CLLD7 or sequences complementary or substantially homologous thereto or fragments thereof. Also provided are sequences comprising hybrid nucleic acid sequences from two or more of the genes. Also provided are nucleic acid expression vectors, polypeptides, antibodies to the polypeptides, host cells, non-human transgenic animals and pharmaceutical compositions and agents. Also provided is the use of the nucleic acid sequence and/or protein in medicine and research, methods for diagnosing or determining predisposition to disease or severity of disease, methods for preventing or treating disease, and kits for use in the methods and the use of the nucleic acid sequence and protein in treating or preventing IgE mediated diseases and non-atopic asthma, and in screens for identifying new agents for use in the methods.
REFERENCES:
patent: 6979549 (2005-12-01), Masuda et al.
patent: 1 329 029 (2002-01-01), None
patent: 1 376 679 (2002-10-01), None
patent: WO 97/33909 (1997-09-01), None
patent: WO 99/04265 (1999-01-01), None
patent: WO 99/18210 (1999-04-01), None
patent: WO 99/38973 (1999-08-01), None
patent: WO 00/58473 (2000-10-01), None
patent: WO 00/60077 (2000-10-01), None
patent: WO 01/60860 (2001-08-01), None
patent: WO 01/70979 (2001-09-01), None
patent: WO 01/79556 (2001-10-01), None
patent: WO 02/068579 (2002-09-01), None
patent: WO 02/079404 (2002-10-01), None
patent: WO 03/052048 (2003-06-01), None
patent: WO 2004/007671 (2004-01-01), None
Cory et al. 1974; Inhibitors of Histone Methylation. Chem.-Biol. Interactions 9: 253-259.
Mabuchi et al.(Apr. 1, 2001. Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphatic leukemia. Cancer Research 61:2870-2877.
Lee et al. 1977; Phosphorylation and methylation of chromatin proteins from mouse brain nuclei. J. Neurocheminstry 29: 547-550.
Wallwork et al.1978; A sensitive assay for histone methyltransferase. Analytical Biochemistry 84: 103-110.
Vandel et al. 2001 ; Physcial assoication between the histone acetyl transferase CBP and a histone methyl transferase. EMBO Reports. 2(1): 21-26.
Database EMBL Online, Jan. 7, 2000, Database accession No. AB011031.
Database EMBL Online, Sep. 29, 2000, Database accession No. AK026228.
Reference SNP Cluster Report, Online, Jan. 29, 2001, rs1046295, Retrieved from the Internet.
Database EMBL Online, Mar. 1, 2001, Database accession No. AL139321.
Database EMBL Online, Mar. 4, 2000, Database accession No. H83343.
Database EMBL Online, Feb. 6, 2000, Database accession No. AW387566.
Bhattacharyya et al., “A High-Density Genetic Map of the Chromosome 13q14 Atopy Locus,”Genomics70:286-291 (2000).
Mabuchi et al., “Cloning and Characterization of CLLD6, CLLD7, and CLLD8, Novel Candidate Genes for Leukemogenesis at Chromosome 13q14, a Region Commonly Deleted in B-Cell Chronic Lymphocytic Leukemia,”Cancer Research61:2870-2877 (2001).
Palmer et al., “Using single nucleotide polymorphisms as a means to understanding the pathophysiology of asthma,”Respir. Res. 2:102-112 (2001).
Scanlan et al., “Antigens Recognized by Autologous Antibody in Patients With Renal-Cell Carcinoma,”Int. J. Cancer83:456-464 (1999).
Aasland et al., “The PHD finger: Implications for chromatin-mediated transcriptional regulation,”TIBS, 1995, 20:56-59.
Abecasis et al., “A General Test of Association for Quantitative Traits in Nuclear Families,”Am. J. Hum. Genet., 2000, 66:279-292.
Abecasis and Cookson, “GOLD-Graphical Overview of Linking Disequilibrium,”Bioinformatics, 2000, 16(2):182-183.
Abecasis et al., “Merlin-rapid analysis of dense genetic maps using sparse gene flow trees,”Nature Genetics, 2002, 30:97-101.
Abecasis et al., “The Power to Detect Linkage Disequilibrium with Quantitative Traits in Selected Samples,”Am. J. Hum. Genet., 2001, 68:1463-1474.
Abecasis et al., “Extent and Distribution of Linkage Disequilibrium in Three Genomic Regions,”Am. J. Hum. Genet., 2001, 68:191-197.
Altschul et al., “Gapped Blast and PSI-Blast: a new generation of protein database search programs,”Nucl. Acids Res., 1997, 25(17):3389-3402.
Anderson et al., “Positive association to IgE levels and a physical map of the 13q14 atopy locus,”Eur. J. Hum. Genet., 2002, 10:266-270.
Angioni et al., “Interstitial Insertion ofAF10into theALLIGene in a Case of Infant Acute Lymphoblastic Leukemia,”Cancer Genet. Cytogenet., 1998, 107:107-110.
Bentley et al., “The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and x,”Nature, 2001, 409:942-943.
Beyer et al., “Evidence for Linkage of Chromosome 5q31-q33 and 13q12-q14 Markers to Atopic Dermatitis,”J. Allergy Clin. Immunol., 1998, p. S152, Abstract No. 631.
Bhattacharyya et al., “A High-Density Genetic Map of the Chromosome 13q14 Atopy Locus,”Genomics, 2000, 70:286-291.
Burge and Karlin, “Prediction of Complete Gene Structures in Human Genomic DNA,”J. Mol. Biol., 1997, 268:78-94.
Chesi et al., “The t(4;14) Translocation in Myeloma Dysregulates BothFGFR3and a Novel Gene,MMSET, Resulting in IgH/MMSET Hybrid Transcripts,”Blood, 1998, 92(9):3025-3034.
Cookson and Palmer, “Investigating the asthma phenotype,”Clin. Exp. Allergy, 1998, 28(Suppl. 1):88-89.
Cookson, “The alliance of genes and environment in asthma and allergy,”Nature, 1999, 402(Supp):B5-B11.
Cox et al., “Association of atopic dermatitis to the beta subunit of the high affinity immunoglobulin E receptor,”Br. J. Dermatol., 1998, 138:182-187.
Daniels et al., “A genome-wide search for quantitative trait loci underlying asthma,”Nature, 1996, 383:247-250.
Dizier et al., “Detection of a Recessive Major Gene for High IgE Levels Acting Independently of Specific Response to Allergens,”Genetic Epidemiology, 1995, 12:93-105.
Duffy et al., “Genetics of Asthma and Hay Fever in Australian Twins,”Am. Rev. Respir. Dis., 1990, 142:1351-1358.
Eiberg et al., “Linkage relationship between the human immunoglobulin-E polymorphism and marker systems,”Cytogenetics and Cell Genetics, 1985, 42:622, Abstract.
Fair et al., “Protein Interactions of the MLL PHD Fingers Modulate MLL Target Gene Regulation in Human Cells,”Mol. Cell. Biol., 2001, 21(10):3589-3597.
Flint et al., “Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the α globin cluster,”Hum. Mol. Genet., 2001, 10(4):371-382.
Garlisi et al., “A Unique mRNA Initiated within a Middle Intron ofWHSC1/MMSETEncodes a DNA Binding Protein That Suppresses HumanIL-5Transcription,”Am. J. Respir. Cell Mol. Biol., 2001, 24:90-98.
Gerrard et al., “A Genetic Study of Immunoglobulin E,”Am. J. Hum. Genet., 1978, 30:46-58.
Hill et al., “FcεRl-βpolymorphism and risk of atopy in a general population sample,”BMJ, 1995, 311:776-779.
Hizawa et al., “Genetic regulation ofDermatophagoides pteronyssinus-specific IgE responsiveness: A genome-wide multipoint linkage analysis in families recruited through 2 asthmatic sibs,”J. Allergy Clin. Immunol., 1998, 102:436-442.
Jarvis and Burney, “The epidemiology of allergic disease,”BMJ, 1998, 316:607-610.
Jenuwein, “Re-SET-ting heterochromatin by histone methyltransferases,”Trends Cell Biol. 2001, 11(6):266-273.
Jurka, “Repbase Update. a database and an electronic journal of repetitive elements,”TIG, 2000, 16(9):418-420.
Kalachikov et al., “Cloning and Gene Mapping of the Chromosome 13q14 Region Deleted in Chronic Lymphocytic Leukemia,”Genomics, 1997, 42:369-377.
Kimura et al., “Linkage and association of atopic asthma to markers on chromosome 13 in the
Cookson William
Moffatt Miriam
Tinsley Jon
Zhang Youming
Carlson Karen Cochrane
Fish & Richardson P.C.
Isis Innovation Limited
LandOfFree
ANGE gene in atopy does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with ANGE gene in atopy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and ANGE gene in atopy will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2787423