Anesthetic polyorganophosphazenes

Details Anesthetic polyorganophosphazenes Anesthetic polyorganophosphazenes

1984-09-21

1987-01-13

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

546 22, 560 46, 560 49, 564 12, 564 13, 514110, 514118, 514124, 424 78, C08G 7902, C08G 7904, A61K 958

Patent

active

046363874

ABSTRACT:
A long-acting, local anesthetic, comprising a polymeric phosphazene backbone, and certain radicals having local anesthetic activity and an amino functional group on the ring of said radical through which said radical is covalently attached to the phosphazene backbone by a phosphorous-nitrogen single bond is disclosed along with medicaments containing such anesthetics. The radicals employed are 2-amino-4-picoline, benoxinate, naepaine and phenacaine.

REFERENCES:
patent: 3914283 (1975-10-01), Okamoto et al.
patent: 4495174 (1985-01-01), Allcock et al.
Allcock et al., Chemical Abstracts, vol. 97, No. 2, Abst. No. 6898-Y (Jul. 12, 1982).
Allcock et al., Chemical Abstracts, vol. 102, No. 20, Abst. No. 172,651d, (May 20, 1985).

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