Anesthetic polyorganophosphazenes

Details Anesthetic polyorganophosphazenes Anesthetic polyorganophosphazenes

1982-06-21

1985-01-22

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

560 48, 560 64, 546 22, 564 12, 564 13, A61K 958, C08G 7902, C08G 7904

Patent

active

044951744

ABSTRACT:
A long-acting, local anesthetic, comprising a polymeric phosphazene backbone, and 2-amino-4-picoline radical having local anesthetic activity and an amino functional group on the ring of said radical through which said radical is covalently attached to the phosphazene backbone by a phosphorous-nitrogen single bond is disclosed along with medicaments containing such anesthetics.

REFERENCES:
patent: 4055523 (1977-10-01), Dieck et al.
patent: 4130547 (1978-12-01), Fieldhouse
patent: 4207403 (1980-06-01), Cheng et al.
patent: 4218557 (1980-08-01), Hergenrother et al.
patent: 4221904 (1980-09-01), Hergenrother et al.
patent: 4223102 (1980-09-01), Hergenrother et al.
patent: 4242491 (1980-12-01), Hergenrother et al.
Wilson and Grisvold "Textbook of Organic Medicinal and Pharmaceutical Chemistry, Second Edition, pp. 411-434, Lippincott Co. Pub. (1954).

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