Anesthetic composition and method of using the same

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514326, 514818, A61K 31445

Patent

active

048596850

ABSTRACT:
There is disclosed an injectable anesthetic pharmaceutical composition which does not exhibit muscle rigidity and which includes an anesthetic effective amount of at least one substituted N-(4-piperidinyl)-N-amide and a muscle rigidity inhibiting effective amount of at least one alpha-2 adrenergic agonist as principle ingredients. Also disclosed are methods of inducing and maintaining anesthesia without muscle rigidity by administering said composition to warm blooded animals.

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patent: 4659714 (1987-04-01), Watt-Smith
Flacke et al, Chem. Abst., vol. 98, #191,500u (1983).
Ghignono et al., Biosis, vol. 80, #105332.
Zimpfer et al, Biosis, vol. 82, #283417.
Malec et al, Chem. Abst., vol. 91, #49486f (1979).

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