Anesthetic composition and method of using the same

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ether doai

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A61K 3108

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active

047628561

ABSTRACT:
The present invention is directed to an anestesia inducing composition comprising a mixture of oxygen gas and an anesthesia inducing effective amount of a compound 2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane having the formula ##STR1## The present invention is also directed to methods of inducing and/or maintaining anesthesia by administering the composition in sufficient amounts to warm blooded animals.

REFERENCES:
patent: 3535425 (1970-10-01), Terrell et al.
patent: 3609196 (1971-09-01), Terrell
patent: 3764705 (1973-10-01), Terrell
patent: 3897502 (1975-07-01), Russell et al.
patent: 3980714 (1976-09-01), Siegemund
patent: 4113883 (1978-09-01), Bagnall
patent: 4559154 (1985-12-01), Powell
Bart, A. J. et al. "Changes in Power of Electroencephalograms During Anesthesia with Fluroxene, Methoxyflurane and Ethrane38 (Feb. 1971), 11 pages.
Koblin, D. D. et al. "Minimum Alveolar Concentrations and Oil/Gas Partition Coefficients of Four Anestheitc Isomers" (Apr. 1981), 4 pages.
R. Terrell, "Halogenated Methyl Ethyl Ethers as Anesthetic Agents" Oct. 10, 1970 (pp. 517-519) J. Med. Chem., 14(6) (Jun. 1971).
R. Terrell, "Fluorinated Methyl Ethyl Ethers as Anesthetic Agents" Dec. 6, 1971 (pp. 604-606) J. Med. Chem., 15(6) (Jun. 1972).
P. E. Aldrich and William A. Sheppard, "Fluorinated Ethers, II. Alkyl Fluoroalkyl Ethers.sup.1 " Jul. 1, 1963 (pp. 11-15) J. Org. Chem., 29(14) (Jan. 1964).
K. K. Johri and D. D. DesMarteau, "Comparison of the Reactivity of CF.sub.3 OX(X.dbd.Cl,F) with some Simple Alkenes", Jul. 26, 1982 (pp. 242-250) J. Org. Chem., 48(2) 1983.

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