Androgen receptor complex-associated protein

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S069100, C530S350000

Reexamination Certificate

active

07083935

ABSTRACT:
The invention relates to new proteins that bind to and aide the transactivation activity of androgen receptors, and nucleic acids encoding them.

REFERENCES:
patent: 1106690 (2001-06-01), None
patent: WO 97/44490 (1997-11-01), None
patent: WO22/04152 (2000-01-01), None
patent: WO 01/07471 (2001-02-01), None
patent: WO 01/53315 (2001-07-01), None
Decision by the Prime Minister: “Goal of Project”. Regarding Millennium Project (New Millennium Project). pp. 58 and 62, Dec. 19, 1999 (with English Abstract.).
R. W. Ould (translated by Motoaki Anai). Principle of Genetic Engineering, 3rdEdition, pp. 115, lines 15-20, Apr. 20, 1997 (with English Abstract.).
Miyamoto, et al.Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DUl45 cells. Proc. Natl. Acad. Sci. 95:7379-7384, Jun. 1998.
Moilanen, et al.Identification of a novel RING finger protein as a coregulator in steroid receptor-mediated gene transcription. Molecular and Cellular Biology 18(9):5128-5139, 1998.
Akira, et al.Protein inhibitor of activatored STAT3 regulated androgen receptor singaling in prostate carcinoma cells. Biochemical and Biophysical Research Comunications 278(1):9-13, Nov. 2000.
Kang, et al.Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor. Journal of Biological Chemistry 274(13):8570-8576, Mar. 1999.
Miguel Beato, “Gene Regulation by Steroid Hormones”, Feb. 10, 1989, Cell, vol. 56;335-344.
Chen et al., “Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300”, Aug. 8, 1997, Cell, vol. 90;569-580.
Lui et al., “Analysis of Glucocorticoid Receptors in Human Hepatocellular Carcinoma and HepG2 cells”, Nov. 4, 1993, Hepatology, vol. 18;1167-1174.
Bert O'Malley, “The Steriod Receptor Superfamily: More Excitement Predicted for the Future”, Mol Endo, vol. 4 No. 3;363-369.

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