Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2006-02-07
2006-02-07
Helms, Larry R. (Department: 1642)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C536S023100, C536S023500, C536S024310, C536S024330, C435S320100, C435S325000
Reexamination Certificate
active
06994992
ABSTRACT:
The invention provides novel AS3 nucleic acid sequences, AS3 polypeptides, anti-AS3 antibodies, and methods for modulating cell proliferation and detecting compounds that modulate cell proliferation. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
REFERENCES:
patent: WO 9731531 (1997-09-01), None
Rae, FK, et al, 2000, Novel association of a diverse range of genes with renal cell carcinoma as identiified by differential display, Internal Journal of Cancer, vol. 88, No. 5, pp. 726-732.
Database GenBank Accession No. BF509252, National Cancer Institute—Cancer Genome Anatomy Project, Unpublished, 1997, UI-H-B I4-aow-c-07-0-UI.s1 NCI13CGAP13Sub 8Homo sapienscDNA clone.
Database GenBank Accession No. U95825, Geck, P, et al, Direct Submission, Mar. 28, 1997, Human androgen-induced prostate proliferative shutoff associated protein (AS3) mRNA, complete cds.
Tockman, MS, et al, 1992, Considerations in bringing a cancer biomarker to clinical application, Cancer Research, vol. 52, Suppl., pp. 2711s-2718s.
Cawthon, RM, et al, 1991, cDNA sequence and genomic structure of EV12B, a gene lying within an intron of the neurofibromatosis type 1 gene, Genomics, vol. 9, pp. 446-460.
Ward, AM, 1985, Tumour Markers, Developmental Oncology, vol. 21, pp. 90-106.
Database GenBank Accession No. AB023196, Ohara, et al, Direct Submission, Feb. 4, 1999,Homo sapiensmRNA for KIAA0979 protein, partial cds.
Database GenBank Accession No. AC068224, Birren, et al, Direct Submission, Apr. 30, 2000,Homo sapienschromosome 3 clone RP-1-660H19 map 3, Low-Pass Sequence Sampling.
Database GenBank Accession No. AB014548, Ohara, el al, Direct Submission, May 26, 1998,Homo sapiensmRNA for KIAA0648 protein, partial cds.
Database GenBank Accession No U50533, Simard, Direct Submission, Mar. 4, 1996, Human BRCA2 region, mRNA sequence CG008.
Bowie, JU, et al, 1990, Deciphering the message in protein sequences: tolerance to amino acid substitutions, Science, vol. 247, pp. 1306-1310.
Burgess, WH, et al, 1990, Possible dissociation of the heparin-binding and mitogenic activities of heparin-binding (acidic fibroblast) growth factor-1, J Cell Biology, vol. 111, pp. 2129-2138.
Lazar, E, et al, 1988, Transforming growth factor alpha: mutation of aspartic acid 47 and leucine 48 results in different biological activities, Molecular and Cellular Biology, vol. 8, pp. 1247-1252.
Critchfield GC. Disease Markers. 1999; 15: 108-11.
Gura T. Science. Nov. 7, 1997; 278: 1041-2.
Boehringer Mannhein Biochemicals 1994 Catalog, p. 93.
Promega 1993/1994 Biological Research Products Catalog, p. 149.
Skolnick J, et al. Trends Biotechnol. 2000; 18: 34-9.
Bergers G, et al. Curr. Opin. Genetics Develop. 2000; 10: 120-7.
Terpe K. Appl Microbiol Biotechnol. 2003; 60: 523-33.
Knappik A, et al. Biotechniques. Oct. 1994; 17 (4): 754-61.
Bendig MM. Genetic Eng. 1988; 7: 91-127.
Database EMBL Nucleotide and Protein Sequences Sep. 11, 1996, AC=U50553. Human BRCA2 region.
Database EMBL Nucleotide and Protein Sequences Jan. 30, 1997, AC=Z84572. Human DNA sequence from PAC 49J10, BRCA2 gene region chromosome 13q12-13 contains ESTs.
Database EMBL Nucleotide and Protein Sequences Nov. 1, 1999, AC=Q9Y215 KIAA0979 Protien (Fragment).
Database EMBL Nucleotide and Protein Sequences Jan. 25, 2000, AC=AL137201 Novel human gene mapping to chromosome 13.
Database EMBL Nucleotide and Protein Sequences Mar. 31, 1999, AC=U95825, Human androgen-induced prostate proliferative shutoff associated protein (AS3) mRNA.
Denison SH, et al. Mutation in the bimD gene ofAsprgillus nidulansconfers a conditional mitotic block and sensitivity to DNA damaging agents.Genetics. Aug. 1993;134(4):1085-96.
Geck P, et al. Expression of novel genes linked to the androgen-induced, proliferative shutoff in prostate cancer cells.J Steroid Biochem Mol Biol.Nov.-Dec. 1997;63(4-6):211-8.
Geck P, et al. Early gene expression during androgen-induced inhibition of proliferation of prostate cancer cells: a new suppressor candidate on chromosome 13, in the BRCA2-Rb1 locus,J Steroid Biochem Mol Biol.Jan. 1999;68(1-2);41-50.
Koch C, et al. A role for the transcription factors Mbp1 and Swi4 in progression from G1 to S phase.Science.Sep. 17, 1993;261(5128):1551-7.
Sadar MD, et al. Prostate cancer: molecular biology of early progression to androgen independence.Endocr Relat Cancer.Dec. 1999;6(4):487-502.
Soto AM, et al. Variants of the human prostate LNCaP cell line as tools to study discrete components of the androgen-mediated proliferative response.Oncol Res.1995;7(10-11):545-58.
Soto AM, et al. The role of estrogens on the proliferation of human breast tumor cells (MCF-7).J Steroid Biochem.Jul. 1985;23(1):87-94.
Thiessen EU. Concerning a familial association between breast cancer and both prostatic and uterine malignancies.Cancer.Oct. 1974;34(4):1102-7.
Tulinius H, et al. Risk of prostate, ovarian, and endometrial cancer among relatives of women with breast cancer.BMJ.Oct. 10, 1992;305(6858):855-7.
Waddick KG, et al. Innovative treatment programs against cancer: II: Nuclear factor-kappaB (NF-kappaB) as a molecular target.Biochem Pharmacol.Jan. 1, 1999;57(1):9-17.
Zhang Y, et al. Molecular characterization of the cyclin-dependent kinase inhibitor p27 promoter.Biochim Biophys Acta.Sep. 12, 1997;1353(3):307-17.
Geck Peter
Sonnenschein Carlos
Soto Ana M.
Szelei Jozsef
Guterman Sonia K.
Helms Larry R.
Lawson & Weitzen, LLP
Rawlings Stephen L.
Trustees of Tufts College
LandOfFree
Androgen-induced suppressor of cell proliferation and uses... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Androgen-induced suppressor of cell proliferation and uses..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Androgen-induced suppressor of cell proliferation and uses... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3698153