Anaphylatoxin receptor ligands containing lipophilic residues

Details Anaphylatoxin receptor ligands containing lipophilic residues Anaphylatoxin receptor ligands containing lipophilic residues

1994-07-12

1997-09-02

Davenport, Avis M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 18, 514 16, 530328, 530329, 530330, 530331, A61K 3800, C07K 500, C07K 700, C07K 1700

Patent

active

056631480

ABSTRACT:
Oligopeptide compounds or oligopeptide analague compounds of the formula, A-B-D-E-G-J-L-M-N(R.sup.4)Arg-OH, which are ligands for the anaphylatoxin receptor and are useful in the treatment of inflammatory disease states, as well as anaphylatoxin receptor ligand compositions and a method for modulating anaphylatoxin activity.

REFERENCES:
patent: 5223485 (1993-06-01), Kawai et al.
Gerard et al., Journal of Immunology, vol. 127, No. 5, Nov. 1981, pp. 1978-1982.
Ember et al., Journal of Immunology, vol. 148, No. 10, May 15, 1992, pp. 3165-3173.

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