Anandamide amidase inhibitors as analgesic agents

Details Anandamide amidase inhibitors as analgesic agents Anandamide amidase inhibitors as analgesic agents

1997-11-12

1999-02-23

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514507, 514528, 514613, 514617, 514629, 548545, 554 37, 562874, A61K 3140, A61K 3121, C07C23502, C07D20746

Patent

active

058744592

ABSTRACT:
Disclosed is a method of inhibiting anandamide amidase in an individual or animal and novel inhibitors of anandamide amidase. The disclosed method and novel compounds can be used to reduce pain in an individual or animal suffering from pain, reducing nausea in an individual undergoing chemotherapy, for example cancer chemotherapy, suppressing appetite in an individual, reducing intraocular pressure in the eye of an individual or animal suffering from glaucoma and suppressing the immune system in an individual with an organ transplant.

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