Analyzing time modulated electrospray

Details Analyzing time modulated electrospray Analyzing time modulated electrospray

1994-02-22

1995-07-25

Berman, Jack I.

Radiant energy

Ionic separation or analysis

With sample supply means

250286, H01J 4910

Patent

active

054364469

ABSTRACT:
A system for forming a time modulated electrospray from a sample solution is provided. Further systems for analyzing this time modulated electrospray also are provided. An element connected to a time modulated voltage source is positioned substantially opposite an electrospray apparatus and an analytical apparatus so that the initial direction of travel of the electrospray is reversed and the electrospray is diverted into the analytical apparatus. A second time modulated voltage can be provided which causes the periodic deflection of an ion beam, resulting from a time modulated electrospray, into a mass analyzer in a vacuum system. The modulation of this second voltage source is coordinated with the time modulation of the first voltage source which causes the formation of an electrospray in such a manner that efficiency of sample introduction into the mass analyzer is improved.

REFERENCES:
patent: 4542293 (1985-09-01), Fenn et al.
patent: 4968888 (1990-11-01), Appelhans et al.
patent: 5070240 (1991-12-01), Lee et al.
patent: 5171990 (1992-12-01), Mylchreest et al.
patent: 5306410 (1994-04-01), Jarrell et al.

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