Analyzing system with disposable calibration device

Details Analyzing system with disposable calibration device Analyzing system with disposable calibration device

1997-08-01

2000-04-04

Manuel, George

Surgery

Diagnostic testing

Measurement of skin parameters

600315, A61B 500

Patent

active

060455020

ABSTRACT:
A system and method for calibrating a measurement instrument prior to making a measurement on a material or tissue includes utilizing a removable calibration device to calibrate the instrument, then removing a target portion of the calibration device so that a measurement may be performed. The calibration device may include an index matching agent, such as a gel, that is to be interposed between the patient's skin and an output end of the measuring instrument. A method embodying the invention may include making a bilirubin concentration measurement on a skin of a patient by measuring the amplitude of light reflected from the patient's skin at first and second wavelengths indicative of a blood content of the patient's skin, and measuring the amplitude of reflected light at a third wavelength indicative of an uncorrected bilirubin concentration, then calculating a corrected bilirubin concentration based on the three measurements. The method may also include taking measurements at fourth and fifth wavelengths indicative of a melanin content of the patient's skin, and calculating the bilirubin concentration based on the fourth and fifth measurements.

REFERENCES:
patent: 4029085 (1977-06-01), DeWitt et al.
patent: 5353790 (1994-10-01), Jacques et al.
patent: 5792049 (1998-08-01), Eppstein et al.

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