Analytical test strip apparatus

Chemistry: physical processes – Physical processes – Crystallization

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Details

23253R, 23259, G01N 2700, G01N 3100, G01N 3300

Patent

active

040652637

ABSTRACT:
Analytical test strip apparatus for chemical, physical and biological experiments on small samples of fluids or fluid-like materials, consists of a thin, flat, hollow, pliable strip the interior including a channel completely filled with a thin layer of an inert liquid, preferably of a grease like consistency, into which liquid is introduced a small amount of the fluid to be tested, to form a movable "blister". The blister is propelled through the inert liquid, which confines it at all times front and rear, by applied external pressure. A plurality of chemical, physical, biological or detection stations are typically located in said channel. A physical station might consist of a filter membrane; a chemical station of a small pocket of chemical reagent; a detecting station of a material sensitive to pH. The stations are confined by the inert liquid filling the interior channel of the strip. In addition to forming the front and rear walls of the movable blister, the inert liquid also prevents migration of reagent located in a station, excludes air and other matters and prevents escape of noxious material being analyzed. In operation, a small portion of fluid is introduced into the strip top and the top is pinched to form a bubble or blister therein. The pinch line is drawn down the strip length forcing the blister ahead of it. As the blister proceeds down the tube, it is subjected to chemical, physical, biological and detecting operations as it passes through the different stations. One side of the tube being preferably transparent, results of the operations may be visible to the eye.

REFERENCES:
patent: 3036894 (1962-05-01), Forestiere
patent: 3552928 (1971-01-01), Fetter
patent: 3620678 (1971-11-01), Gurgan et al.
patent: 3689224 (1972-09-01), Agneu et al.
patent: 3697227 (1972-10-01), Goldstein et al.
patent: 3713779 (1973-01-01), Sieago et al.
patent: 3776515 (1969-11-01), Johnson et al.
patent: 3917453 (1975-11-01), Milligan et al.

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