Analytical test device with substrate having oriented...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S091500, C435S970000, C435S973000, C436S514000, C436S518000, C436S538000, C436S528000, C436S165000, C436S810000, C436S805000

Reexamination Certificate

active

06849408

ABSTRACT:
The present invention is directed to methods for analyzing one or more fluid samples for the presence, amount or identity of one or more analytes optionally present in said samples, which uses a device having one or more round wells with a fixed diameter, the wells exposing a substrate of a specific thickness, whereby the substrate has oriented through going channels, in the area of the substrate exposed in the well is provided with at least one binding substance specific for a least one of said analytes. Using the device the sample fluid is forced to pass through the channels in the substrate from the upper side of the substrate to the lower side of the substrate and back at least one time, under conditions that are favorable to a reaction between any analyte present in the sample and the binding substances.

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Rigby et al., “An Anodizing Process for the Production of Inorganic Microfiltration Membranes,” Trans. Inst. Metal Finish, 1990, vol. 68, (3), pp. 95-98.

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