Analytical test device and the use thereof

Chemistry: analytical and immunological testing – Optical result – With claimed manipulation of container to effect reaction or...

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436178, 422 56, 422 57, 422 58, 435 71, G01N 2100

Patent

active

051067587

ABSTRACT:
The analytical device includes a base adapted to support a porous member having dispersed throughout at least one analyte responsive substance which undergoes a detectable response to the presence and concentration of the analyte in the test sample. A cover integral with the base is provided with a reaction well adapted for storing a dried reaction component and for receiving the liquid test sample deposited on the analytical device whereby the liquid test sample and the reaction component form a liquid reaction mixture therein. A passage is included in the reaction well for selectively transferring the reaction mixture therethrough. This passage is normally spaced from the porous member and effectively closed to transfer therethrough of the reaction mixture, and is selectively movable toward the porous member to effectively open to passage therethrough of the reaction mixture whereby the analyte responsive substance will undergo a detectable response to the analyte present in the liquid reaction mixture. The base is provided with a suitable viewing port to permit monitoring of the detectable response generated as a result of the at least one analyte responsive substance interacting with the analyte in the test sample. Such a detectable response may be detected by appropriate photometric or colorimetric apparatus.

REFERENCES:
patent: 4323536 (1982-04-01), Columbus
patent: 4668472 (1987-05-01), Sakamoto et al.
patent: 4717656 (1988-01-01), Swanljung
patent: 4738823 (1988-04-01), Engelmann
patent: 4920046 (1990-04-01), McFarland et al.

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