Analytical test composition, device and method for the determina

Details Analytical test composition, device and method for the determina Analytical test composition, device and method for the determina

1983-04-04

1984-05-08

Turk, Arnold

Chemistry: analytical and immunological testing

Hemoglobin, myoglobin, or occult blood

422 56, 427 2, 435 28, 436904, G01N 3352, G01N 3372

Patent

active

044475420

ABSTRACT:
A test composition, device and method for determining a peroxidatively active substance in a test sample, as well as a method for preparing the device, are disclosed. The composition comprises an organic hydroperoxide and an indicator capable of providing a detectable response in the presence of the organic hydroperoxide and peroxidatively active substance, wherein the organic hydroperoxide is a substituted cumene hydroperoxide having the formula: ##STR1## in which any one of the X substituents is lower alkyl of from 1 to 6 carbon atoms, Cl, Br, I, NO.sub.2 or carboxyl; or any two of the X substituents, same or different, are lower alkyl of from 1 to 6 carbon atoms, Cl, Br, I, NO.sub.2 or carboxyl. The device comprises a carrier matrix incorporated with the composition, and the method comprises contacting a test sample with the device and observing a detectable response in the device. A method for preparing the device comprises preparing a solution of the composition, wetting the carrier matrix therewith and drying the wetted matrix.

REFERENCES:
patent: 3012976 (1961-12-01), Adams, Jr. et al.
patent: 3252762 (1966-05-01), Adams, Jr. et al.
patent: 4372746 (1983-02-01), Habenstein
patent: 4386053 (1983-05-01), Motobayashi

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