Radiant energy – Ionic separation or analysis – With sample supply means
Reexamination Certificate
2008-02-26
2010-11-09
Vanore, David A (Department: 2881)
Radiant energy
Ionic separation or analysis
With sample supply means
C250S281000, C250S282000, C250S284000, C250S287000
Reexamination Certificate
active
07829846
ABSTRACT:
The present invention achieves accurate quantitative determination without reducing measurement throughput and also without having to add a multi-component reference standard. An analytical instrument of the present invention for determining the concentration of a target compound contained in a target sample includes: a means for ionizing a mixture having a specific compound added to the target sample; a means for performing mass analysis on resulting ions; and a database that stores dependence of signal intensity on the concentration of a specific matrix component for each of the target compound and the addition compound, wherein the database is used to calibrate the concentration of the target compound from a signal derived from the target compound and a signal derived from the addition compound, each signal obtained by the mass analysis means. The present invention achieves a multi-component analyzer using low-cost, high-throughput mass analysis, as compared to conventional technique.
REFERENCES:
patent: 5037764 (1991-08-01), Wilk et al.
patent: 5481476 (1996-01-01), Windig
patent: 5498545 (1996-03-01), Vestal
patent: 5572025 (1996-11-01), Cotter et al.
patent: 5572125 (1996-11-01), Dunkel
patent: 5644503 (1997-07-01), Ito et al.
patent: 5726064 (1998-03-01), Robinson et al.
patent: 6393368 (2002-05-01), Ito et al.
patent: 6449584 (2002-09-01), Bertrand et al.
patent: 6539102 (2003-03-01), Anderson et al.
patent: 6545268 (2003-04-01), Verentchikov et al.
patent: 6580067 (2003-06-01), Yamada et al.
patent: 6632655 (2003-10-01), Mehta et al.
patent: 6707035 (2004-03-01), Hughey et al.
patent: 6867415 (2005-03-01), Hughey et al.
patent: 6930305 (2005-08-01), Covey et al.
patent: 6940065 (2005-09-01), Graber et al.
patent: 7038197 (2006-05-01), Bateman et al.
patent: 7075064 (2006-07-01), Oliphant et al.
patent: 7110886 (2006-09-01), Ito et al.
patent: 7138625 (2006-11-01), Overney et al.
patent: 7232689 (2007-06-01), Pawliszyn
patent: 7279679 (2007-10-01), Old et al.
patent: 7356446 (2008-04-01), Ito et al.
patent: 7373256 (2008-05-01), Nicholson et al.
patent: 7388194 (2008-06-01), Schneider et al.
patent: 7473892 (2009-01-01), Sano et al.
patent: 7493225 (2009-02-01), Wang et al.
patent: 7529629 (2009-05-01), Wang
patent: 7577538 (2009-08-01), Wang
patent: 7645984 (2010-01-01), Gorenstein et al.
patent: 7667195 (2010-02-01), Vestal
patent: 7668658 (2010-02-01), Koster et al.
patent: 2009/0325311 (2009-12-01), Lecerf et al.
Xu et al., “Comparison of conventional and enhanced mass resolution triple-quadrupole mass spectrometers for discovery bioanalytical applications”, Rapid Communications in Mass Spectrometry, 17,832, 2003.
Ito et al., “Matrix effect and correction by standard addition in quantitative liquid chromatographic-mass spectrometric analysis of diarrhetic shellfish poisoning toxins”, J. Chromatography A 943, 39, 2001.
Bonfiglio et al., “The effects of sample preparation methods on the variability of the electrospray ionization response for model drug compounds”, Rapid Communications in Mass Spectrometry, 13(12), 1175, 1999.
Hasegawa Hideki
Hashimoto Yuichiro
Sugiyama Masuyuki
Takada Yasuaki
Antonelli, Terry Stout & Kraus, LLP.
Hitachi , Ltd.
Vanore David A
LandOfFree
Analytical system and method utilizing the dependence of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Analytical system and method utilizing the dependence of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Analytical system and method utilizing the dependence of... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4220084