Analytical methods and probes for the identification of chromoso

Details Analytical methods and probes for the identification of chromoso Analytical methods and probes for the identification of chromoso

1994-10-18

1997-10-21

Fleisher, Mindy

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

4351723, C12Q 168, C12N 1501

Patent

active

056795173

ABSTRACT:
Methods for identifying the existence, and optionally the location, of chromosomal aberration(s) in the genome of an organism are disclosed. Intact, chromosomal DNA is hybridized with one or more clones constructed from chromosomal DNA derived from an organism of the same species as the organism to be tested. By identifying the existence of a chromosomal aberration, the susceptibility of an individual to certain disease states can be predicted, and/or the nature of a given disease state can be ascertained with greater certainty.

REFERENCES:
Griffin et al. (1986), Proc. Natl. Acad. Sci. USA 83 : 6122-6126.

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