Analytical markers for malignant breast cancer

Chemistry: molecular biology and microbiology – Vector – per se

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536 235, C12N 1570, C07H 2104

Patent

active

052368440

ABSTRACT:
The present invention relates to a gene encoding a new member of the metalloproteinase family which has been found to be specifically associated with invasive breast cancer, and to methods of diagnosis for such cancer comprising detection of the marker or its nucleotide sequence, and to treatment or prophylaxis by inhibiting, altering the activity of or binding the marker, or by interfering with its synthesis.

REFERENCES:
Chen et al (1990, Sep.) Oncoqche 5(9) 1391-5.
Davis et al (1987) P.N.A.S. 81, 2194-2198.
Salomon et al., in Breast Cancer: Cellular and Molecular Biology (eds., Lippman, M. E. and Dickson, R. B.), pp. 363-389 (Kluwer, Boston, (1988).

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