Chemistry: molecular biology and microbiology – Vector – per se
Patent
1991-11-21
1993-08-17
Moskowitz, Margaret
Chemistry: molecular biology and microbiology
Vector, per se
536 235, C12N 1570, C07H 2104
Patent
active
052368440
ABSTRACT:
The present invention relates to a gene encoding a new member of the metalloproteinase family which has been found to be specifically associated with invasive breast cancer, and to methods of diagnosis for such cancer comprising detection of the marker or its nucleotide sequence, and to treatment or prophylaxis by inhibiting, altering the activity of or binding the marker, or by interfering with its synthesis.
REFERENCES:
Chen et al (1990, Sep.) Oncoqche 5(9) 1391-5.
Davis et al (1987) P.N.A.S. 81, 2194-2198.
Salomon et al., in Breast Cancer: Cellular and Molecular Biology (eds., Lippman, M. E. and Dickson, R. B.), pp. 363-389 (Kluwer, Boston, (1988).
Basset Paul
Bellocq Jean-Pierre
Chambon Pierre
Bennett Lisa
Centre National de Recherche Scientifique
Institut National de la Sante et de la Recherche Medicale
Moskowitz Margaret
Universite Louis Pasteur Strasbourg
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