Analytical element for measurements of enzyme activity

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving oxidoreductase

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435 16, 435 25, 436169, 436170, 422 56, 422 60, C12Q 128, C12Q 126, C12Q 152

Patent

active

055081738

ABSTRACT:
A multilayer analytical element for measuring enzyme activity in a liquid sample such as a body fluid which is less affected by intrinsic pyruvic acid contained in the liquid sample is disclosed. The analytical element comprises a support, a reagent layer, an optionally provided other layer, and a porous spreading layer. The reagent layer and/or the optionally provided other layer contain pyruvic acid oxidase. The characteristic feature of the analytical element lies in that the spreading layer has a specific void volume in the range of 3-15 .mu.l/cm.sup.2.

REFERENCES:
patent: 4503145 (1985-03-01), Katsuyama et al.
patent: 4786595 (1988-11-01), Arai et al.

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