Analytical element for determination of hydrogen peroxide and an

Details Analytical element for determination of hydrogen peroxide and an Analytical element for determination of hydrogen peroxide and an

1987-11-05

1990-12-18

Warden, Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving uric acid

435 11, 435 14, 435 16, 435 25, 435 28, 435805, 435810, 436169, 436170, 422 56, 422 60, 422 61, C12Q 161, C12Q 128, C12Q 126, C12Q 154

Patent

active

049786121

ABSTRACT:
Disclosed is an analytical element for determination of hydrogen peroxide, which comprises using an analytical element containing a substance having the action of peroxidation, a compound represented by Formula (I) shown below, and an aromatic primary amine compound, or a salt thereof, capable of forming a dye through the coupling reaction with the compound represented by Formula (I) shown below: ##STR1## wherein Z represents a group of nonmetallic atoms necessary for forming a nitrogen-containing heterocyclic ring, which ring formed by Z may have a substituent; X represents a hydrogen atom or a group capable of being split off through the reaction with an oxidized product of the aromatic primary amine compound; and R represents a hydrogen atom or a substituent.
Disclosed is also an analytical method for determination of hydrogen peroxide by use of the above analytical element.
As described in the foregoing, the analytical element of this invention can exhibit the remarkable effect that the determination sensitivity can be greatly improved.

REFERENCES:
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patent: 4278439 (1981-07-01), White
patent: 4418037 (1983-11-01), Katsuyama et al.
patent: 4460684 (1984-07-01), Bauer
patent: 4665023 (1987-05-01), Deneke et al.
patent: 4672029 (1987-06-01), Washburn et al.
patent: 4721670 (1988-01-01), Osada et al.
patent: 4732736 (1988-03-01), Kobayashi et al.
patent: 4849342 (1989-07-01), Ben-Michael

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