Analytical element containing photosensitive compound and filter

Details Analytical element containing photosensitive compound and filter Analytical element containing photosensitive compound and filter

1986-02-18

1988-11-29

Warden, Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving transferase

435 7, 435 28, 435805, 422 56, C12Q 150, C12Q 128, G01N 148

Patent

active

047881402

ABSTRACT:
A multilayer analytical element for the determination of a clinically significant enzyme analyte comprises a photosensitive compound (e.g. a photosensitive dye or dye precursor) and a filter layer containing one or more filter dyes. The filter layer is situated in the element such that incident radiation used to detect a density change resulting from interaction of the analyte and the photosensitive compound passes through the filter layer before it reaches the photosensitive compound. The use of the filter layer inhibits premature changes in the photosensitive compound caused by incident radiation. This element is particularly useful for the determination of creatine kinase or one of its isoenzymes, e.g. creatine kinase-MB.

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patent: 4387160 (1983-06-01), Gomez et al.
patent: 4430436 (1984-02-01), Koyama et al.
patent: 4478944 (1984-10-01), Gross et al.
patent: 4547461 (1985-10-01), Esders et al.

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