Analytical device for membrane-based assays

Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Calorimeter

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422 57, 422 58, 422 59, 422 60, 436518, G01N 33543

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active

058855262

ABSTRACT:
An analytical device is provided. The device comprises a liquid-impervious top support layer that defines a rim around an open port. A porous reaction membrane having an upper surface and a lower surface is proximal to the top support layer, such that a portion of the reaction membrane upper surface and rim define a sample receiving well. The reaction membrane upper surface is sealed to the lower surface of the top support layer by water-insoluble adhesive so as to form a liquid-impervious seal therebetween. An absorbent body is proximal to and in liquid communication with the lower surface of the reaction membrane. The analytical device may further comprise a liquid-impervious bottom support layer which is attached to the lower surface of the absorbent body. The device can be used in immunoassays for the detection of a bindable substance in a liquid sample containing the target substance.

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