Analytical apparatus utilizing a colorimetric or other optically

Details Analytical apparatus utilizing a colorimetric or other optically Analytical apparatus utilizing a colorimetric or other optically

1995-06-05

1997-04-22

Snay, Jeffrey

Chemistry: analytical and immunological testing

Measurement includes temperature change of the material...

436151, 436164, 422 8202, 422 8209, 2503383, 356432, G01N 2100

Patent

active

056228686

ABSTRACT:
Analytical apparatus includes a pyroelectric or other thermo-electric transducer element (10) in strip form. Thin film electrodes (12,14) are provided and one or more dots of reagent (16) are deposited on the transducer surface. A small amount of biological or other sample is deposited over the reagent dots which undergo selective colorimetric changes. The transducer is illuminated from below by LED light sources (24) and light absorption in the reagent regions is detected as microscopic heating at the transducer surface. The electrical signal output from the pyroelectric transducer is processed to derive analyte information.

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Coufal et al. "Pyroelectric Calorimeter for Photothermal Studies of Thin Films and Adsorbates" Journal of Vacuum Science & Technology, vol. 5, No. 5, pp. 2875-2889 (1987).
Tanaka et al. "Pyroelectric Photothermal Spectroscopy for Thin Solid Films" Journal of Applied Physics, vol. 63, No. 6, pp. 1815-1819 (1988).

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