Analyte-substitute reagent for use in specific binding assay met

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals

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422 50, 422 56, 422 60, 435 793, 435971, 435973, 435975, 436514, 436538, 436540, 436816, 436817, 436822, G01N 33543

Patent

active

055019854

ABSTRACT:
Assay reagents, devices, methods and kits used in the analysis of low molecular weight analytes which by themselves are too small or unable to bind to two specific binding members at the same time. The invention involves the use of an analyte-substitute reagent (ASR) comprising at least two components, the first of which is identical to or an analog of the analyte to be determined, while the second is an unrelated ligand for which an antibody or other specific binding member can be obtained or produced.

REFERENCES:
patent: 4446232 (1984-05-01), Liotta
patent: 4496654 (1985-01-01), Katz et al.
patent: 4803170 (1989-07-01), Stanton et al.
patent: 5340748 (1994-08-01), Baugher et al.

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