Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...
Reexamination Certificate
2006-11-28
2006-11-28
Olsen, Kaj K. (Department: 1753)
Chemistry: electrical and wave energy
Processes and products
Electrophoresis or electro-osmosis processes and electrolyte...
C204S600000
Reexamination Certificate
active
07141152
ABSTRACT:
A analyte species separation system including a fluid flow field disposed between confining surfaces, the flow field having a first flow component flowing in a first direction and a second flow component flowing in a second, transverse, direction, and an electric field configured to cause analyte species to move in the separation flow field at least in a direction opposite to the first flow component, a analyte injection channel in fluid communication with the flow field and an analyte separation target channel or otherwise a collector in fluid communication with the flow field, the system configure so that an analyte species in an analyte sample injected into the flow field traverses at least a portion of the flow field toward the collector target channel with said second flow component, enabling analyte species separation parallel to the first direction and movement in the second direction so that analyte species having mobilities outside a selected mobility range do not enter the target channel and/or an analyte species having a selected mobility is directed into the target channel.
REFERENCES:
patent: 4323439 (1982-04-01), O'Farrell
patent: 4698142 (1987-10-01), Muroi et al.
patent: 5092972 (1992-03-01), Ghowsi
patent: 5151164 (1992-09-01), Blanchard et al.
patent: 5180475 (1993-01-01), Young et al.
patent: 5180480 (1993-01-01), Manz
patent: 5262031 (1993-11-01), Lux et al.
patent: 5282942 (1994-02-01), Herrick et al.
patent: 5320730 (1994-06-01), Ewing et al.
patent: 5441613 (1995-08-01), McCormick et al.
patent: 5482608 (1996-01-01), Keely et al.
patent: 5728282 (1998-03-01), Bashkin et al.
patent: 5750015 (1998-05-01), Soane et al.
patent: 5800690 (1998-09-01), Chow et al.
patent: 5810985 (1998-09-01), Bao et al.
patent: 5882465 (1999-03-01), McReynolds
patent: 5900934 (1999-05-01), Gilby et al.
patent: 5948227 (1999-09-01), Dubrow
patent: 5955028 (1999-09-01), Chow
patent: 5957579 (1999-09-01), Kopf-Sill et al.
patent: 5958202 (1999-09-01), Regnier et al.
patent: 5958203 (1999-09-01), Parce et al.
patent: 5958694 (1999-09-01), Nikiforov
patent: 5959291 (1999-09-01), Jensen
patent: 5964995 (1999-10-01), Nikiforov et al.
patent: 5965001 (1999-10-01), Chow et al.
patent: 5965410 (1999-10-01), Chow et al.
patent: 5972187 (1999-10-01), Parce et al.
patent: 5976336 (1999-11-01), Dubrow et al.
patent: 5989402 (1999-11-01), Chow et al.
patent: 6001229 (1999-12-01), Ramsey
patent: 6010608 (2000-01-01), Ramsey
patent: 6277258 (2001-08-01), Ivory et al.
Manz et al, J. Micromech. Microeng. 4 (1994), pp. 257-265.
Zheng Huang & Cornelius F. Ivory, Digitally Controlled Electrophoretic Focusing, Anal. Chem. 1999, 71, 1628-1632.
Robert D. Greenlee & Cornelius F. Ivory, Protein Focusing in a Conductivity Gradient, Biotechnol. Prog. 1998, 14, 300-309.
Charles R. Cantor, Cassandra L. Smith & Matthew K. Mathew, Pulsed-field Gel Electrophoresis of Very Large DNA Molecules, Ann. Rev. Biophys. Biophys. Chem 1998 17:287-304.
Peter F. Gavin & Andrew G. Ewing, Continuous Separations with Microfabricated Electrophoresis—Electrochemical Array Detection, J.Am. Chem. Soc 1996, 117, 8932-8936.
J.M. Mesaros, P.F. Gavin, & A.G. Ewing, Flow Injection Analysis Using Continuous Channel Electrophoresis, Flow Injection Analysis Using Continuous Channel Electrophoresis, Anal. Chem. 1996, 68, 3441-3449.
Stellan Hjerten, Jia-Li Liao, & Ron Zhang, New approaches to concentration on a microliter scale of dilute samples, particularly biopolymers with special reference to analysis of peptides and proteins by capillary electrophoresis, Journal of Chromatography A.676 (1994) 409-420.
J.M. Mesaros, G. Luo, J. Roeraade, & A.G. Ewing, Continuous Electrophoretic Separations in Narrow Channels Coupled to Small-Bore Capillaries, Anal. Chem. 1993, 65, 3313-3319.
Andras Guttman, Bart Wanders, & Nelson Cooke, Enhanced Separation of DNA Restriction Fragments by Capillary Gel Electrophoresis Using Field Strength Gradients, Anal. Chem. 1992, 64, 2348-2351.
Tshenge Demana, Maureen Lanan, & Michael D. Morris, Improved Separation of Nucleic Acids with Analyte Velocity Modulation Capillary Electrophoresis, Anal. Chem. 1991, 63, 2795-2797.
Cornelius F. Ivory & William A. Goble, Continuous Counteracting Chromatographic Electrophoresis, Biotechnol. Prog. 1990, 6, 21-32.
Bruce R. Locke & Ruben G. Carbonell, A Theoretical and Experimental Study of Counteracting Chromatographic Electrophoresis, Separation & Purification Methods, 18(1), 1-64 (1989).
Timothy C. Scott, Use of Electric Fields in Solvent Extraction: A Review and Prospectus, Separation & Purification Methods, 18(1), 65-109 (1989).
W. Ansorge & S. Labeit, Field gradients improve resolution on DNA sequencing gels, Journal of Biochemical & Biophysical Methods, 10 (1984) 237-243.
M.D. Biggin, T.J. Gibson & G.F. Hong, Buffer gradient gels and35S label as an aid to rapid DNA sequence determination, Proc. Natl, Acad. Sci., vol. 80, pp. 3963-3965, Jul. 1983C.
Dennison, W.A. Lindner, & N.C. Phillips, Nonuniform Field Gel Electrophoresis, Analytical BioChemistry 120, 12-18 (1982).
Patrick H. O'Farrell, J. Biol. Science vol. 227 Mar. 198 ? Separation Techniques Based on the Opposition of Two Counteracting Forces to Produce a Dynamic Equilibrium.
Wendy S. Koegler, Cornelius F. Ivory, Focusing proteins in an electric field gradient, Journal of Chromatography A, 229 (1996) 229-236.
Olsen Kaj K.
Thorpe North & Western LLP
LandOfFree
Analyte species separation system does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Analyte species separation system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Analyte species separation system will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3660777