Analyte detection system

Details Analyte detection system Analyte detection system

2005-01-04

2005-01-04

Snay, Jeffrey R. (Department: 1743)

Chemistry: analytical and immunological testing

Optical result

With fluorescence or luminescence

C422S082070, C422S082080, C250S458100, C250S459100

Reexamination Certificate

active

06838289

ABSTRACT:
An analyte detection system utilizing a combination of fluorescent labels for labeling particles and an analyte specific fluorescent analyte detection dye. The particles contain a combination of fluorescent labels for coding the particles and an analyte specific fluorescent dye. The particles can be used to identify and quantify analytes in an analytical sample by reaction of the analytical sample with the particles. An analytical device can identify the particles according to the combination of fluorescent labels. The device can then correlate the identified particle with the analyte specific fluorescent analyte detection dye. Multiple subpopulations of particles can be used to identify and quantify multi-analytes in a single analytical sample. Near infrared (NIR) fluorescent labels useful in the detection system are also provided.

REFERENCES:
patent: 2887479 (1959-05-01), Heseltine
patent: 2895955 (1959-07-01), Heseltine et al.
patent: 4256834 (1981-03-01), Zuk et al.
patent: 4318707 (1982-03-01), Litman et al.
patent: 4325706 (1982-04-01), Gershman et al.
patent: 4499052 (1985-02-01), Fulwyler
patent: 4609689 (1986-09-01), Schwartz et al.
patent: 4661913 (1987-04-01), Wu et al.
patent: 4719182 (1988-01-01), Burdick et al.
patent: 4729947 (1988-03-01), Middendorf et al.
patent: 4745285 (1988-05-01), Recktenwald et al.
patent: 4772561 (1988-09-01), Genshaw
patent: 4839265 (1989-06-01), Ohno et al.
patent: 4882265 (1989-11-01), Lagaanis et al.
patent: 4933269 (1990-06-01), Parton et al.
patent: 4973572 (1990-11-01), DeBoer
patent: 5028545 (1991-07-01), Soini
patent: 5037734 (1991-08-01), Lenhard et al.
patent: 5061618 (1991-10-01), Parton et al.
patent: 5162863 (1992-11-01), Ito
patent: 5207880 (1993-05-01), Middendorf et al.
patent: 5268486 (1993-12-01), Waggoner et al.
patent: 5312921 (1994-05-01), Glazer et al.
patent: 5321130 (1994-06-01), Yue et al.
patent: 5366603 (1994-11-01), Middendorf et al.
patent: 5375606 (1994-12-01), Slezak et al.
patent: 5410030 (1995-04-01), Yue et al.
patent: 5556959 (1996-09-01), Brush et al.
patent: 5571388 (1996-11-01), Patonay et al.
patent: 5573909 (1996-11-01), Singer et al.
patent: 5585241 (1996-12-01), Lindmo
patent: 5627040 (1997-05-01), Bierre et al.
patent: 5682038 (1997-10-01), Hoffman
patent: 5736330 (1998-04-01), Fulton
patent: 5747349 (1998-05-01), van den Engh et al.
patent: 5763189 (1998-06-01), Buechler et al.
patent: 5808044 (1998-09-01), Brush et al.
patent: 5880474 (1999-03-01), Norton et al.
patent: 5986086 (1999-11-01), Brush et al.
patent: 6027709 (2000-02-01), Little et al.
patent: 6028190 (2000-02-01), Mathies et al.
patent: 6048982 (2000-04-01), Waggoner
patent: 6130094 (2000-10-01), Waggoner et al.
patent: 6159748 (2000-12-01), Hechinger
patent: 6406667 (2002-06-01), Singh et al.
patent: 0 609 894 (1994-08-01), None
patent: 0 670 374 (1995-09-01), None
patent: 0 753 584 (1996-07-01), None
patent: 0 670 374 (1998-05-01), None
patent: WO 9919515 (1999-04-01), None
patent: WO 9937814 (1999-07-01), None
Strekowski, Lucjan,Substitution Reactions of a Nucleofugal Group in Heptamethine Cyanine Dyes. Synthesis of an Isothiocyanota Derivative for Labeling of Proteins with a Near-Infrared Chromophore,J. Org. Chem. 57, 4578-4580 (1992).
Slominskii, Y.L.,Polymethine Dyes with Hydrocarbon Bridges, Enamino Ketones in the Chemistry of Cyanine Dyes,Journal of Organic Chemistry of the USSR, vol. 19, No. 10, pp. 2134-2142 (1983).
Strekowski, Lucjan,Facile Derivations of Heptamethine Cyanine Dyes,Synthetic Communications, 22(17), 2593-2598 (1992).
Slominskii, Y.L.,Tricarbocyanines with Hydrogen Rings in the Chromophore,Journal of Organic Chemistry of the USSR, vol. 40, No. 6, pp. 625-628 (1974).
Arnold, Z.,Synthetic Reactions of Dimethylformamide. XXII. Formation and Preparation of Formyl Derivatives of Indene, Collection Czechoslov. Chem. Commun.,vol. 30, 2783-2792 (1965).
Reynolds, G.A.,Stable Heptamethine Pyrylium Dyes That Absorb in the Infrared,J. Org. Chem., vol. 42, No. 5, 885-888 (1977).
Sosnovskii, G.M.,Synthesis of Meso-Substituted Tricarbocyanine Dyes With An Ortho-Phenylene Bridge In The Chromophore,Journal of Organic Chemistry of the USSR, vol. 19, No. 10, 1861-1864 (1983).
Makin, S.M.,Aminoformylation of Unsaturated Aldehydes 2-Alkoxyaldehyes and Their Acetals, and Keytones of the Alicyclic Series,Journal of Organic Chemistry of the USSR, vol. 13, No. 6, 1093-1096 (1977).
Webb, J.P.,Sixteen New Infrared Laser Dyes Excited By A Simple Linear Flashlamp,Eastman Organic Chemical Bulletin, vol. 46, No. 3, 1-6 (1974).
Russian reference by Tolmachev et al. (full cite is in Russian).
Narayanan, N.,New Method for the Synthesis for Heptamethine Cyanine Dyes: Synthesis of New Near-Infrared Fluorescent Labels,J. Org. Chem. 60, 2391-2395 (1995).
Strekowski, L.,Functionalization of Near-Infrared Cyanine Dyes, .Heterocyclic Chem., 33, 1685-1688 (1996).
Narayanan, N.,New Near Infrared Dyes for Applications in Bioanalytical Methods,SPIC vol. 2388, 6-15 (1995).
Pierce, Brian M.,Lasing Properties of Several Near-IR Dyes for a Nitrogen laser-Pumped Dye Laser with an Optical Amplifier,IEEE Journal of Quantum Electronics, vol. QE-18, No. 7 (1982).

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