Measuring and testing – Gas analysis – Gas chromatography
Patent
1974-03-12
1977-01-18
Yudkoff, Norman
Measuring and testing
Gas analysis
Gas chromatography
23230R, 23230B, 23230M, 23231, 23232R, 23232C, 23254R, 55 67, 55 74, 55197, 73 611C, G01N 3106, G01N 3108, G01N 3302, G01N 3316
Patent
active
040032574
ABSTRACT:
System and method for reproducibly analyzing, both qualitatively and quantitatively, trace amounts of a large number of organic volatiles existing in a gas sample. Applications include (1) analyzing the headspace gas of body fluids and comparing a profile of the oganic volatiles with standard profiles for the detection and monitoring of disease, (2) analyzing the headspace gas of foods and beverages and comparing a profile of the organic volatiles with standard profiles so that flavor and aroma can be monitored and controlled, and (3) similar analysis for determining the organic pollutants in samples of water and air.
The system includes a novel means (sample trap) for capturing and enriching the organic volatiles, a novel injector port for directly injecting the entrapped organic volatiles to a cryogenic percolumn to provide a sharply defined plug, and a novel capillary separating column. Various detectors may be utilized to identify the separated volatiles.
The sample trap contains a solid adsorbent having the following properties: (1) high affinity for volatile organic compounds, (2) hydrophobic, (3) temperature stability up to 400.degree. C, (4) good desorption capability and (5) relative inertness to the sample. A porous material based on a polymer of 2,6-diphenyl-p-phenylene oxide (PPPO) and sold under the trademark TENAX-GC is particularly suited for this purpose. The injector port is formed of a hollow body having inlet and outlet ports. The sample trap is inserted into the body and maintained in sealed engagement with the outlet port. The injector port is placed into an injector heater of a gas chromatograph (GC) to effect desorption of the entrapped volatiles. Helium gas is introduced at the inlet port to carry the organic volatiles directly into the cryogenic precolumn. The GC capillary separating column is formed of etched nickel which facilitates the separation of a large number of specific organic compounds from a very small amount of organic volatiles.
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Fletcher James C. Administrator of the National Aeronautics and Space
Zlatkis Albert
Hollander Barry I.
Manning John R.
Matthews Marvin F.
Schlorff Russell E.
Yudkoff Norman
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