Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving oxidoreductase
Patent
1981-08-31
1985-10-29
Naff, David M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving oxidoreductase
435 25, 435189, 435805, 435885, C12Q 126, C12Q 128, C12N 902, C12R 146
Patent
active
RE0320161
ABSTRACT:
Compositions and multilayer analytical elements comprising lactate oxidase which is substantially free of catalase and preferably produced by Streptococcus faecalis ATCC 12755 are provided for the quantitative analysis of lactic acid or lactate, especially in serum. The lactate oxidase catalyzes the reduction of lactic acid or lactate to pyruvate and hydrogen peroxide and the quantity of lactic acid or lactate is determined by detecting the amount of hydrogen peroxide produced. Preferably, the hydrogen peroxide is detected colorimetrically using a peroxidase-catalyzed detection system.
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Dixon et al., Enzyme, Academic Press Inc., Publishers, New York (1964), pp, 680 & 681.
Esders Theodore W.
Goodhue Charles T.
Schubert Richard M.
Eastman Kodak Company
Naff David M.
Tucker J. Lanny
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