Analysis of DNA

Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Biological or biochemical

Reexamination Certificate

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Reexamination Certificate

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07668660

ABSTRACT:
The invention provides methods for providing information on the probability of DNA samples being contaminated over days, weeks and months in relation to collection, processing and analysis of DNA samples. Methods are also provided for analysing the likelihood of a result arising due to contamination and/or determining the analysis protocol to be applied to a DNA sample and/or methods of operating databases, particularly containing DNA profiles.Improvements in accounting for sporadic and undetected contamination and improvements in the operation of DNA sampling of analysis are provided by the invention.

REFERENCES:
patent: 2002/0007248 (2002-01-01), Gill et al.
patent: 2006/0281134 (2006-12-01), Love
Gill, P. et al. “Development of a Simulation Model to Assess the Impact of Contamination in Casework Using STRs,” Journal of Forensic Sciences, 49(3):485-491, May 2004.
Gill, P. “Role of Short Tandem Repeat DNA in Forensic Casework in the UK-Past, Present, and Future Perspectives,” Biotechniques, 32(2):366-385, Feb. 2002.
Gill, P. et al. “An investigation of the rigor of interpretation rules for STRs derived from less than 100 pg of DNA,” Forensic Science International, 112(1):17-40, Jul. 2000.
Rutty, G. et al. “DNA contamination of mortuary instruments and work surfaces: a significant problem in forensic practice?” International Journal of Legal Medicine, 114(1-2):56-60, Dec. 2000.

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