Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2001-08-01
2010-06-22
Woodward, Cherie M (Department: 1647)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S410000, C435S468000
Reexamination Certificate
active
07741049
ABSTRACT:
The present invention provides a method for analyzing agonist-activity to a cytokinin receptor, which comprises (1) bringing an examinee substance into contact with a transformed cell into which DNA coding the cytokinin receptor is introduced and(2) measuring the existence or the quantity of intracellular signal transduction from the cytokinin receptor expressed in the transformed cell, and, a method for analyzing antagonist-activity to a cytokinin receptor, which comprises (1) bringing an examinee substance and a substance having agonist-activity to the cytokinin receptor into contact with a transformed cell into which DNA coding the cytokinin receptor is introduced and(2) measuring the existence or the quantity of intracellular signal transduction from the cytokinin receptor expressed in the transformed cell, and the like.
REFERENCES:
patent: 5194596 (1993-03-01), Tischer et al.
patent: 5350836 (1994-09-01), Kopchick et al.
patent: 6077682 (2000-06-01), Inouye et al.
patent: 6245970 (2001-06-01), Frommer
patent: 7026530 (2006-04-01), Benfey et al.
patent: 2002/0173017 (2002-11-01), Benfey et al.
patent: 0 892 063 (1999-01-01), None
patent: 1033405 (2000-09-01), None
patent: WO 99/36508 (1999-07-01), None
patent: WO 02/099079 (2002-12-01), None
Iwamura et al. (1983), Quantitative Aspects of the Receptor Binding of Cytokinin Agonists and Antagonists, J. Medicinal Chem., vol. 26, No. 6, pp. 838-844.
Rashotte et al. (2003), Expression Profiling of Cytokinin Action inArabidopsis, Plant Physiology, vol. 132, pp. 1998-2011.
Estelle (1998), Cytokinin action: Two receptors better than one? Current Biology, vol. 8, pp. R539-R541.
Schaller (1997), Ethylene and cytokinin signalling in plants: the role of two-component systems, Essays Biochem. vol. 32, pp. 101-111.
Haberer et al. (2002), Cytokinins. New Insights into a Classic Phytohormone, Plant Physiology 128: 354-362.
Iwamura et al., 1983, J Medicinal Chem. 26(6): 838-844 (copy provided with Office Action of Jan. 6, 2004).
Bowie et al. Science. 1990. 247:1306-1310.
Wells. Biochemistry 1990. 29:8509-8517.
Holland et al., Biosystems. 1987; 20(2):181-206, Abstract Only.
Skolnick et al. 2000, Trends in Biotech. 18:34-39.
Bork. 2000, Genome Research 10:398-400.
Doerks et al. 1998, Trends in Genetics 14:248-250.
Smith et al. 1997, Nature Biotechnology 15:1222-1223.
Brenner. 1999, Trends in Genetics 15:132-133.
Bork et al. 1996, Trends in Genetics 12:425-427.
Benjamin et al., 1998, Development 125:1591-1598.
Vukicevic et al. 1996, PNAS USA 93:9021-9026.
Massague. 1987, Cell 49:437-8.
Pilbeam et al., 1993, Bone 14:717-720.
T. Kakimoto, “Cytokinin signaling”, Current Opinion in Plant Biology, Quadrant Subscription Services, GB, vol. 5, No. 1, 1998, pp. 399-403 (Abstract XP-001079011).
M. Estelle, “Cytokinin action: Two receptors better than one?”, Current Biology, Current Science, GB, vol. 16, No. 8, 1998, pp. R539-R541 (Abstract XP-001071265).
Kulaeva et al., “A new family of cytokinin receptors from Cereales”, FEBS Letters, vol. 423, No. 2, Feb. 20, 1998, pp. 239-242 (Abstract XP-002212288).
T. Inoue et al., “Identification of CRE1 as a cytokinin receptor fromArabidopsis”, Nature, vol. 409, No. 6823, (Feb. 22, 2001), pp. 1060-1063 with Abstract XP-002199637.
A. P. Mahonen et al., “A novel two-component hybrid molecule regulates vascular morphogenesis of theArabidopsisroot”, Genes & Development, vol. 14, No. 23, (Dec. 1, 2001), pp. 2938-2943.
T. Kakimoto, “CKI1, a Histidine Kinase Homolog Implicated in Cytokinin Signal Transduction”, Science, American Association for the Advancement of Science, vol. 274, (Nov. 8, 1996), pp. 982-985.
Kakimoto et al., “2SF4 Roles of histidine kinases in cytokinin signal transduction”,Biophysics The biophysical Society of Japan, vol. 40, Supplement 1, Aug. 5, 2000, p. S111, with English translation and accompanying Declaration.
Inoue et al., “W1D3 A study on cytokinin signal transduction”,Program Workshop Abstracts of the 23rdAnnual Meeting of The Molecular Biology Society of Japan, Dec. 2000, p. 259, with English translation and accompanying Declaration.
Machida et al., “W1D-6 Plant cell growth controlled by the MAP kinase cascade mediated by NPK1 MAPKKK”,Program Workshop Abstracts of the 23rdAnnual Meeting of The Molecular Biology Society of Japan, Dec. 2000, p. 259, with English translation and accompanying Declaration.
Inoue et al., “4PC-312 Mutation in the histidine kinase gene T23K3.2 causes cytokinin-insensitive phenotype”,Program Workshop Abstracts of the 23rdAnnual Meeting of The Molecular Biology Society of Japan, Dec. 2000, p. 816, with English translation and accompanying Declaration.
Huguchi et al., “4PC-313 The product of the causal gene T23K3.2 for the cytokinin insensitive mutant functions as a cytokinin receptor in yeast,”Program Workshop Abstracts of the 23rdAnnual Meeting of The Molecular Biology Society of Japan, Dec. 2000, p. 817, with English translation and accompanying Declaration.
Kakimoto et al., “Success In Isolating A Receptor Of Cytokinin Which Increases Plant Growth, Onto Developing Agrochemicals”,Nikkei Biotech, Mar. 12, 2001, p. 12, with English translation and accompanying Declaration.
Inoue et al., “Identification of CRE1 as a cytokinin receptor fromArabidopsis,” Nature, vol. 409, Feb. 22, 2001, pp. 1060-1063.
Ueguchi et al., “Novel Family of Sensor Histidine Kinase Genes inArabidopsis thaliana”, Plant Cell Physiol., vol. 42, No. 2, 2001, pp. 231-125.
Suzuki et al., “TheArabidopsisSensor His-kinase, AHK4, Can Respond to Cytokinins”,Plant Cell Physiol., vol. 42, No. 2, 2001, pp. 107-113.
Maeda et al., “A two-component system that regulates an osmosensing MAP kinase cascade in yeast”,Nature, vol. 369, May 19, 1994, pp. 242-245.
Urao et al., “A Transmembrane Hybrid-Type Histidine Kinase inArabidopsisFunctions as an Osmosensor”,The Plant Cell, vol. 11, Sep. 1999, pp. 1743-1754.
Higuchi Masayuki
Inoue Tsutomu
Kakimoto Tatsuo
Sughrue & Mion, PLLC
Sumitomo Chemical Company Limited
Woodward Cherie M
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