Analysis element for determination of a coagulation parameter

Details Analysis element for determination of a coagulation parameter Analysis element for determination of a coagulation parameter

1987-05-04

1989-08-29

Kepplinger, Esther M.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving blood clotting factor

435177, 435176, 435805, 436 69, 436169, 436170, 436810, 422 56, 422 57, 422 58, 422101, C12Q 156, G01N 3386, G01N 148

Patent

active

048617121

ABSTRACT:
The present invention provides an analysis element for the determination of coagulation parameters with the help of a detectable or a detection reaction-initiating substrate of a protease of the blood coagulation system and at least one factor and/or co-factor of the blood coagulation system and a buffer substance, wherein the factor and/or co-factor, together with a water-soluble, non-ionic polymer which does not falsely influence the course of the coagulation cascade, is impregnated on an open, planar composite structure which consists of a material which does not have a disturbing influence on the course of the coagulation.

REFERENCES:
patent: 4473639 (1984-09-01), Sommer et al.
patent: 4477575 (1984-10-01), Vogel et al.
patent: 4557901 (1985-12-01), Koyama et al.
patent: 4610962 (1986-09-01), Takagi et al.
Chemical Abstract 104: 31351.
Chemical Abstract 105: 94109.
Palmer et al., Blood 59(1): 38-42 (1982).
Ogston et al., Brit. Med. Bull. 34(2): 107-112 (1978).

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