Analysing polynucleotide sequences

Details Analysing polynucleotide sequences Analysing polynucleotide sequences

2002-04-04

2010-10-12

Clow, Lori A (Department: 1631)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C536S023100, C536S025300, C422S068100, C435S174000

Reexamination Certificate

active

07811751

ABSTRACT:
This invention provides an apparatus and method for analyzing a polynucleotide sequence, either an unknown sequence or a known sequence. A support carries an array of the whole or a chosen part of a complete set of oligonucleotides, which are capable of taking part in hybridization reactions. The polynucleotide sequence, or fragments thereof, are labeled and applied to the array under hybridizing conditions. Applications include analysis of known point mutations, genomic fingerprinting, linkage analysis, characterization of mRNAs, mRNA populations, and sequence determination.

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