Analogs of thyrotropin-releasing hormone

Details Analogs of thyrotropin-releasing hormone Analogs of thyrotropin-releasing hormone

1975-01-27

1976-05-25

Gotts, Lewis

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424177, C07C10352, A61K 3700

Patent

active

039592480

ABSTRACT:
Novel tripeptides are disclosed. These tripeptides have anti-depressant activity and thyrotropin releasing hormone activity. Processes for preparing these tripeptides are also disclosed.

REFERENCES:
patent: 3912705 (1975-10-01), Fujino et al.
Inouye et al.: Bull. Chem. Soc. Japan, 44, 1689-1691 (1971).
Gillessen et al.: Helv. Chim. Acta, 53, 63-72 (1970).
Gillessen et al.: Helv. Chim. Acta, 54, 1335-1342 (1971).
CHang et al.: J. Med. Chem., 14, 484-487 (1971).
J. M. Stewart and J. D. Young, "SOlid Phase Peptide Synthesis," Freeman and Co., San Francisco, 1969, pp. 1-26.
Beyerman et al.: Rec. Trav. Chim. Pays-Bas, 90, 355-357 (1971).
Boler et al.: J. Med. Chem., 14, 475-476 (1971).
Baugh et al.: Endocrin., 87, 1015-1021 (1970).
Rivier et al.: J. Med. Chem., 479-482 (1972).

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