Analogs of neurohypophysial hormones with inhibition effects

Details Analogs of neurohypophysial hormones with inhibition effects Analogs of neurohypophysial hormones with inhibition effects

1983-06-03

1985-04-02

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C10352, A61K 3700

Patent

active

045086451

ABSTRACT:
The invention pertains to analogs of neurohypophysial hormones evidencing inhibition effects of the chemical formula I ##STR1## where A is CH.sub.3 CO or H, V is a residue of penicilamine or cysteine, B is CH.sub.3 or H, X is a residue of isoleucine or phenylalanine, Y is a residue of penicilamine or cysteine, and Z is a residue of leucine or lysine.
These analogues evidence inhibition effects towards certain biological activities of neurohypophysial hormones.

REFERENCES:
Schroder, et al., The Peptides II, (1966), 320-325, 334, 335, 366-371, 374 & 375.

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