Analogs of hirudin

Details Analogs of hirudin Analogs of hirudin

1990-07-24

1992-06-02

Wax, Robert A.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

435 692, 530855, 514 12, C07K 710

Patent

active

051187906

ABSTRACT:
Compounds and compositions comprising amino acid substituted and chemically modified analogs of hirudin are provided, together with methods for their production and use as antithrombotic and anticoagulant agents.

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Lazar et al., Journal of Biochemistry (1991) 266(2):685-688.
Product Bulletin from SRI International, 333 Ravenswood Avenue, Menlo Park, Calif. entitled "Real-Time Detection and Monitoring of Blood Coagulation" 1 page total.

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