Analogs of growth hormone releasing factor (GRF) and a method fo

Details Analogs of growth hormone releasing factor (GRF) and a method fo Analogs of growth hormone releasing factor (GRF) and a method fo

1989-08-30

1991-06-11

Doll, John

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

530399, C07K 710

Patent

active

050233220

ABSTRACT:
The invention relates to new peptides of the formula ##STR1## wherein R.sup.2 represents Ala or D-Ala,

REFERENCES:
patent: 4518586 (1985-05-01), Rivier et al.
patent: 4528190 (1985-07-01), Vale et al.
patent: 4801456 (1989-01-01), Dmengler
Nature, 300, pp. 276-278 (1982).
Science, 218, pp. 585-587 (1982).
Peptides (ed.: D. Theodoropoulos), N.Y., pp. 481-483 (1987).
Proceedings of the Ninth Am. Peptide Symposium, Pierce Chem. Co., Rockford, Ill., pp. 707-710 (1985).
Biochemical and Biophysical Research Communications, 123 (2), pp. 854-861 (1984).
J. Med. Chem., 28, pp. 181-185 (1985).
Peptides, 7, Suppl. 1, pp. 49-52 (1986).
J. Diary Science, 70, pp. 2511-2517 (1987).
J. Diary Science, 71, pp. 92-100 (1988).
Nature, 300 (11/18/82), 276-278, Rivier et al.

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