Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-10-17
2006-10-17
Davis, Zinna N. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S460000, C549S396000, C549S399000, C549S404000
Reexamination Certificate
active
07122573
ABSTRACT:
Novel compounds useful as chemotherapeutic and chemopreventive agents are provided. The compounds are analogs of polyphenol catechins that occur in green tea, such as epigallocatichin-3-gallate (EGCG), and have the structure of formula (I)wherein R1through R11are defined herein. Preferred R4moieties are selected from O, S, NH and CH2, and in exemplary compounds, R4is O and R5is a tri-substituted aroyloxy substituent, such as a 3,4,5-substituted benzoyloxy group. Pharmaceutical compositions are provided as well, as are methods of chemotherapy and chemoprevention.
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Bensari Ahlem
Chao Wan-Ru
Zaveri Nurulain
Davis Zinna N.
Mintz, Levin, Coh,, Ferris, Glovsky and Popeo, P.C.
SRI - International
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