Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1975-09-02
1976-06-29
Drezin, Norman A.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424 10, 424330, A61K 31485
Patent
active
039669408
ABSTRACT:
Orally effective, analgetic compositions have been developed which are useful in the prevention of drug abuse because upon parenteral administration, they do not produce analgesia, euphoria, or physical dependence. Such compositions comprise an orally active, strong analgetic in oral dosage form and containing, for each analgetic dose of the analgetic agent, an amount of naloxone sufficient, upon parenteral administration of said oral dosage form, to negate the analgetic, euphoretic and dependence producing action of the composition, but insufficient to block the therapeutic effect of the analgetic when the admixture is taken orally.
REFERENCES:
patent: 2770569 (1956-11-01), Fromherz et al.
patent: 3254088 (1966-05-01), Lewenstein et al.
patent: 3466277 (1969-09-01), Merz et al.
patent: 3493657 (1970-02-01), Lewenstein et al.
Goodman et al., Pharm. Basis of Therapeutics, 3rd Edition, (1965), pp. 274-279.
Merck Index 8th Edition, 1968 p. 371.
Gordon Maxwell
Pachter Irwin J.
Bristol-Myers Company
Drezin Norman A.
Havranek Robert E.
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