Analgetic composition

Details Analgetic composition Analgetic composition

1977-03-03

1978-04-11

Moyer, Donald B.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424274, 424267, A61K 31485, A61K 3140

Patent

active

040839818

ABSTRACT:
An analgetic composition which comprises, as an active ingredient, a therapeutically effective amount of a synergistic mixture of an indole-3-acetic acid derivative of the formula, ##STR1## wherein R is a halobenzoyl, piperonylcyl or cinnamoyl group and R.sub.1 is a 5-methoxy or 5,6-methylenedioxy group; and a narcotic or anti-narcotic analgesic selected from the group consisting of a compound of the formula, ##STR2## wherein R.sub.2 and R.sub.3 are each a C.sub.1 - C.sub.3 alkyl group and R.sub.4 is a 4-(4-fluorophenyl)-4-oxobutyl, cyclopropylmethyl or 3-methyl-2-butenyl group; a compound of the formula, ##STR3## wherein R.sub.5 is a hydrogen atom or a C.sub.1 - C.sub.3 alkyl group; a compound of the formula, ##STR4## and a compound of the formula, ##STR5## wherein R.sub.6 is a C.sub.1 - C.sub.3 alkyl group; and a pharmaceutically acceptable carrier or diluent and its preparation and a method of obtaining analgesia which comprises administering the same to a patient.

REFERENCES:
patent: 3161654 (1964-12-01), Shen
patent: 3812112 (1974-05-01), Kimura et al.
patent: 3954986 (1976-05-01), Knoll et al.
patent: 4027024 (1977-05-01), Knoll et al.

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