Analgesic potentiation

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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424274, A61K 3140, A61K 31455

Patent

active

043383246

ABSTRACT:
The analgesic effect of zomepirac is potentiated by simultaneously or sequentially administering to a subject suffering from pain, butorphanol, in a nonanalgesic amount thereby significantly reducing the dosage of zomepirac.

REFERENCES:
patent: 4233313 (1980-11-01), Gardocki
patent: 4233317 (1980-11-01), Gardocki
patent: 4234601 (1980-11-01), Gardocki
Physician's Desk Reference, 34th Ed. (1980), pp. 730-731.
Cooper, S. A., J. Clin. Pharmacol., 20(4), Part 2, 230 (1980).
Wallenstein, S. L. et al. J. Clin. Pharmacol. 20(4) Part 2, 250 (1980).
Gilbert, M. M. et al., J. Int. Med. Res., 6, 14-23 (1978).
Levin, H. M. et al., J. Int. Med. Res., 6 24-33 (1978).

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