Analgesic N-{2-[N'-(2-furylmethyl and 2-thienyl-methyl)-N'-alkyl

Details Analgesic N-{2-[N'-(2-furylmethyl and 2-thienyl-methyl)-N'-alkyl Analgesic N-{2-[N'-(2-furylmethyl and 2-thienyl-methyl)-N'-alkyl

1979-03-08

1980-03-11

Raymond, Richard

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Allergen or component thereof

2603473, 424285, 549 77, 549 74, 549 75, 549 76, A61K 3134, A61K 3138, C07D30754, C07D33324

Patent

active

041928857

ABSTRACT:
Cis- and trans-N-(2-aminocycloaliphatic)benzamide compounds of the formula ##STR1## e.g., N-methyl-N-[2-(N-pyrrolidinyl)cyclohexyl]-3,4-dichlorobenzamide, and their pharmaceutically acceptable salts, have been found to have potent analgesic activity, and compositions containing these compounds useful in pharmaceutical dosage unit form for alleviating pain in warm blooded animals, as well as methods for alleviating pain in animals with these compositions. Processes for preparing the compounds are also disclosed.

REFERENCES:
patent: 3510492 (1970-05-01), Szmuszkovicz
patent: 3647804 (1972-03-01), Rynbrandt et al.
Winternitz et al., Chemical Abstracts, vol. 50 (1956) 14574e.
Brittain et al., British Journal of Pharm., vol. 49 (1973) pp. 158 and 159.
Harper et al., J. Chem. Soc., 1964, p. 4280.

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