Analgesic N-(2-heterocyclic-amino cycloaliphatic) benzamides

Details Analgesic N-(2-heterocyclic-amino cycloaliphatic) benzamides Analgesic N-(2-heterocyclic-amino cycloaliphatic) benzamides

1978-05-10

1980-04-08

Rollins, Alton D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

260239A, 2603264, 544400, 546205, 546234, 424244, 424250, 424267, A61K 3140, C07D20704, C07D29514, A61K 31445

Patent

active

041973089

ABSTRACT:
Cis- and trans-N-(2-aminocycloaliphatic)benzamide compounds of the formula ##STR1## e.g., N-methyl-N-[2-(N-pyrrolidinyl)cyclohexyl]-3,4- dichlorobenzamide, and their pharmaceutically acceptable salts, have been found to have potent analgesic activity, and compositions containing these compounds useful in pharmaceutical dosage unit form for alleviating pain in warm blooded animals, as well as methods for alleviating pain in animals with these compositions. Processes for preparing the compounds are also disclosed.

REFERENCES:
patent: 3510492 (1970-05-01), Szmuszkovicz
patent: 3510505 (1970-05-01), Pribyl et al.
patent: 3647804 (1972-03-01), Rynbrandt et al.
patent: 3652559 (1972-03-01), Szmuskovicz
patent: 3852347 (1974-12-01), Krapcho
patent: 3975443 (1976-08-01), Harper et al.

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