Analgesic N-(2-aminocycloaliphatic)azidobenzamides

Details Analgesic N-(2-aminocycloaliphatic)azidobenzamides Analgesic N-(2-aminocycloaliphatic)azidobenzamides

1978-05-10

1979-12-18

Randolph, John D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

2603264, 2603473, 260349, 544400, 546192, 549 59, 549 69, A61K 31165, C07C11700

Patent

active

041795016

ABSTRACT:
Cis- and trans-N-(2-aminocycloaliphatic)benzamide compounds of the formula ##STR1## e.g., N-methyl-N-[2-(N-pyrrolidinyl)cyclohexyl]-3,4-dichlorobenzamide, and their pharmaceutically acceptable salts, have been found to have potent analgesic activity, and compositions containing these compounds useful in pharmaceutical dosage unit form for alleviating pain in warm blooded animals, as well as methods for alleviating pain in animals with these compositions. Processes for preparing the compounds are also disclosed.

REFERENCES:
patent: 3373195 (1968-03-01), Pribyl et al.
patent: 3499033 (1970-03-01), Szmuszkovicz
patent: 3510492 (1970-05-01), Szmuszkovicz
patent: 3647804 (1972-03-01), Rynbrandt et al.
patent: 3825595 (1974-07-01), Roll
patent: 3847982 (1974-11-01), Herr et al.
patent: 3933497 (1976-01-01), Singh
patent: 3975443 (1976-08-01), Harper et al.
patent: 4098904 (1978-07-01), Szmuszkovicz
Stevens et al., Chemical Abstracts, vol. 75, Abst. No. 88275a (1971).

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