Analgesic N-(2-aminocyclo aliphatic)cyanobenzamides

Details Analgesic N-(2-aminocyclo aliphatic)cyanobenzamides Analgesic N-(2-aminocyclo aliphatic)cyanobenzamides

1978-05-10

1979-04-10

Torrence, Dolph A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

260465D, A61K 31275, C07C12178

Patent

active

041489144

ABSTRACT:
Cis- and trans-N-(2-aminocycloaliphatic)benzamide compounds of the formula ##STR1## e.g., N-methyl-N-[2-(N-pyrrolidinyl)cyclohexyl]-3,4-dichlorobenzamide, and their pharmaceutically acceptable salts, have been found to have potent analgesic activity, and compositions containing these compounds useful in pharmaceutical dosage unit form for alleviating pain in warm blooded animals, as well as methods for alleviating pain in animals with these compositions. Processes for preparing the compounds are also disclosed.

REFERENCES:
patent: 3510492 (1970-05-01), Szmuszkovicz
Harper et al., J. Chem. Soc., p. 4280 (1964).

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