Analgesic method using a morpholine compound

Details Analgesic method using a morpholine compound Analgesic method using a morpholine compound

1980-10-03

1982-11-23

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

42424858, 544171, 544173, 544174, 544152, A61K 31535

Patent

active

043605192

ABSTRACT:
Morpholine derivatives of the formula ##STR1## and their pharmaceutically acceptable acid addition salts[wherein R.sup.1 represents lower alkyl. R.sup.2 represents hydrogen, lower alkyl, benzyl, lower alkoxymethyl or an acyl group; R.sup.3 represents hydrogen, lower alkyl or phenyl; R.sup.4, R.sup.5 and R.sup.6 are independently hydrogen or lower alkyl and R.sup.7 is hydrogen, lower alkyl, lower alkenyl, lower alkynyl, aryl(lower)alkyl, tetrahydrofurylmethyl or cycloalkylmethyl] possess analgesic and/or opiate antagonistic activity.

REFERENCES:
patent: 2997469 (1961-08-01), Heel et al.
patent: 3112311 (1963-11-01), Zimmermann et al.
patent: 3296076 (1967-01-01), Thoma 544173

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