Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-11-08
1998-11-17
Jarvis, William R. A.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514316, 514317, 514400, A61K 31445, A61K 31415
Patent
active
058377166
ABSTRACT:
The present invention discloses that compounds having the formula: ##STR1## wherein Z represents the atoms necessary to complete a five-membered or six-membered heterocyclic ring;
REFERENCES:
patent: 3975530 (1976-08-01), Durant et al.
patent: 4128658 (1978-12-01), Price et al.
patent: 4165377 (1979-08-01), Jones et al.
patent: 4172139 (1979-10-01), Eakins et al.
patent: 4228176 (1980-10-01), Eakins et al.
patent: 4681883 (1987-07-01), Brown et al.
patent: 4705683 (1987-11-01), Dettmar
patent: 4871759 (1989-10-01), Mercer
patent: 5021431 (1991-06-01), Buschauer et al.
patent: 5070101 (1991-12-01), Kaminski
patent: 5221688 (1993-06-01), Clitherow et al.
patent: 5229137 (1993-07-01), Wolfe
patent: 5352688 (1994-10-01), Kaminski
patent: 5403830 (1995-04-01), Place
patent: 5407688 (1995-04-01), Place
Black et al., "Definition and Antagonism of Histamine H.sub.2 -Receptors," Nature, 236:385-390 (1972).
Brimblecombe et al., "Histamine H.sub.2 -Receptor Antagonists," in Goldberg, ed., Pharmacological and Biochemical Properties of Drug Substances, Washington, D.C.: American Pharmaceutical Association Academy of Pharmaceutical Sciences, pp. 329-352 (1977).
Netti et al., "Antinociceptive Effect of Centrally Administered Cimetidine and Dimaprit in the Rat," Pharmacology, 28:262-267 (1984).
Scarpignato et al., "Cimetidine Inhibition of Dimaprit-Induced Writhing in the Rat," Pharmacology, 32:237-240 (1986).
Hough et al., "Cimetidine Penetrates Brain and Inhibits Non-Opiate Footshock-Induced Analgesia," Pharmacology Biochemistry & Behavior, 24:1257-1261 (1986).
Netti et al., "Central Effects of Histamine H.sub.2 -Receptor Agonists and Antagonists on Nociception in the Rat," Agents and Actions, 23:247-249 (1988).
Leza et al., "H.sub.1 -and H.sub.2 -Histamine Receptor Blockers and Opiate Analgesia in Mice," Meth Find Exp Clin Pharmacol, 12:671-678 (1990).
Oluyomi et al., "Involvement of Histamine in Naloxone-Resistant and Naloxone-Sensitive Models of Swim-Stress-Induced Antinociception in the Mouse," Neuropharmacology, 30:1021-1027 (1991).
Lamberti et al., "Investigation Into the Role of Histamine Receptors in Rodent Antinociception," Pharmacology Biochemistry and Behavior, 53(3):567-574 (1996).
Vyas et al, Chemical Abstracts, vol. 92, abstract No. 104279, 1979.
Albany Medical College
Braman, Esq. Susan J.
Jarvis William R. A.
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